Monday, November 26, 2007

Emmalee's Art And Science Fiction



Emmalee poses with her artwork.

----

John broke the antennae off his new remote controlled car after just 1 day of play.

Emmalee said, "We should call Gramma D."

Carolyn said, "This is something daddy will have to fix. Gramma won't be able to help over the phone."

Emmalee said, "But Gramma D can tell John how to fix it."

Carolyn said, "But it's going to have to be soldered. Daddy has to use the soldering iron."

Emmalee said, "But Gramma D knows science"

John said, "Taking things apart and fixing things isn't science"

Emmalee thought about it for a moment and said, "Maybe she knows science fiction..."

(Fiction = Fix-shun)

Emmalee was serious, but we couldn't help but laugh.

Sunday, November 25, 2007

Shopping List Surprise

Carolyn looked at the shopping list and was surprised to see an entry she hadn't made.



Emmalee had surreptitiously added "Wii" to the list -- she spelled it right.

I guess she expected her mom to mindlessly follow the list, see the $250 game system, and buy it without question.

Thursday, November 22, 2007

Kids' Art

A look at our virtual "refrigerator door", a sampling of the kids' art work.



Emmalee's colorful rockets.





John's dream house. The top floor features 40 foot high speakers that dwarf the occupants of the room. This was inspired by John's favorite scene in "Back To The Future"; where Marty McFly hooks up the guitar to Doc's enormous speaker and cranks up the volume. One strum of the electric guitar blows the speaker and blows Marty backwards.

The second floor is a game room.

And the first floor is a Harley Davidson motorcycle garage.

Monday, November 19, 2007

Sunset

Photo Sharing and Video Hosting at Photobucket

John surveys an Indiana sunset.

More pics at our photobucket site

Saturday, November 17, 2007

Happy Birthday, Ted





No, I really didn't get a "New" bike for my birthday. Carolyn and the kids washed up my dirty bike and made it look brand new.






I don't know why I went overboard with the birthday photos this year. I guess I was just playing around with features of www.photobucket.com. Seems pretty cool.

Photobucket Album


Click on the picture for a slide show.

Monday, November 12, 2007

Emmalee's Birthday



A giant chocolate-chip cookie for her birthday...

More pictures

Thursday, November 08, 2007

Sleep Test #2

I had no trouble at all with Sleep Test #1. No anxiety related to being wired in like a Borg.

For #2 everything was the same except there was a CPAP machine with a full-face mask, covering my nose and mouth, and forcing air into my lungs.

I felt as if I was breathing through a straw. I felt as if it could not give me enough air. When I sucked enough air in, it wheezed room air in through the exhalation port. I took all the air sent to me through the pipe, and that wasn't enough, It was exactly like being smothered.

The technician talked to me in dulcet tones trying to calm me down. Convinced I could not smother so long as I could draw air in sharply through the exhaust port -- I laid down and tried to sleep.

Lying still did not help. After about 20 minutes I ripped the mask off and flung it on the ground in frustration. I signalled the technician and waited.

Having trouble? he asked.

I explained that I felt claustrophobic in the mask, I felt like I was suffocating.

He responded in such a soft, hypnotic tone that it angered me. If he could talk to me like a frightened kitten, he did not truly understand my fear or my pain. He did not understand.

Have you ever had anybody get up and walk out?! I asked, with a frantic edge to my voice.

Yes, he replied, but I don't recommend it. It's an insurance nightmare.

I've had my fill of insurance nightmares, and wanted no part of another one.

Would you like a sedative? he asked.

This was creeping me out. I felt like he was not understanding the depth and passion of my feelings. It was like the snake Kaa, mesmerizing his quarry with song and soft voice, only to devour him once he was lulled to sleep.

No! I said, emphatically. I know what those drugs can do. I had visions of myself suffocating to death, unable to raise my own hand to the mask to rip it off. "I don't want a sedative."

Maybe I'd do better with the nasal mask, I relented.

He fitted me to the nasal mask. This one had two nozzles, one per nostril, and strapped to my face like the last one. But my mouth was free. The comfort in this setup was that in a panic I needed only open my mouth to breathe.

I was still very upset. It took a while to calm me down. My body was convinced the nice prison guard was trying to smother me. Every fiber of my being wanted to get up nd flee. I felt as if I was held captive against my will.

I hated this device. I could not imagine using it. I would not ever use it. I only wanted to get through the night so I could be done with this forever.

The first mask was a fat hand held over my mouth and nose, calmly trying to smother me.

The second mask was two snakes trying to crawl up my nose.

The ability to breath through my mouth when necessary helped.

I was ultimately able to fall asleep.

After about two hours of sleep I awoke, with a horrible burning sensation in my nostrils and sinuses. The warm dry air of the devil's breath, breathed into my nostrils by the two-headed demonic serpent, had turned my nasal passages to fire.

I lay there in pain, wanting for all the world the reach up and claw the serpents from my nose, warring with myself, trying to exercise self discipline, trying to keep the test going. For perhaps two more hours I teetered on the edge of sleep, fidgeting, like some horrible hemorroid of the face was perched between my eyes and my mouth.

Finally, in desperation I clawed the mask from my face, flung it to the floor as before. This time, I did not signal the technician.

He came in of his own accord. Speaking hypnotically soft tones to me again.

"Hey, your mask fell off..."

"No, it did not fall off. I took it off."

"Do you want to try a different mask.":

"No," I said flatly. "I want to sleep."

He said okay. We have enough info from the mask, we know what your pressure settings should be. You can go ahead and get some rest. But in 45 minutes it'll be time to get up.

God, have mercy on me. 45 minutes? That makes my total sleep for the night approximately 2:45. Hardly enough to function.

But 45 minutes of sweet sleep without Beelzebub's Spawn trying to violate my face.

I was passive aggressive when the technician awakened me. I would say anything to get him to leave me alone. I had no intention of complying with his suggestions, but I knew that in order to get out of there quickly I had to appear to be compliant.

"Maybe you could get an anti-anxiety medicine to help you adjust to wearing the mask," he said.

"Yeah, maybe" I said, without really agreeing, and with rage rising within me.

God, how can this be your will?

Devil machine

Sleep test with a CPAP machine...




Medieval implements of torture which set my nostrils on fire and clamped a fat hand across my nose and mouth as if to smother me in my sleep. Vile tools of satan bent on my own destruction. In other words. . . I hated it.

Wednesday, October 31, 2007

Tuesday, October 30, 2007

Mom Overture

Sunday, October 28, 2007

The Many Names Of David Ryder

Remember Mystery Science Theater 3000?

Watching "B" movies with your friends, making fun of the cheesy characters and paper-thin plots?

Being a couch potato was never more fun!


Snowboarding

My very own mother alerted me to this very disturbing newsclip, showing the snowboarding phenomenon.

The Road Home

The road home.

Saturday, October 27, 2007

Watseka

Classic midwestern town on a gray october day.



The famous smiley face water tower of Watseka! It was yellow for about 20 years, and recently got repainted white. I wasn't sure they'd apply the smiley face after repainting the tower white, but they did. Watseka will be smiling for another 20 years...



I should've taken this photo from about a half mile closer. The familiar blue silo was built in 1974.

Thursday, October 25, 2007

Sleep Study Results




Monday, October 15, 2007

A Poem By John, Age 8


Dragsters
In a line to race
can hardly wait
finally my turn
things blurring
325 miles per hour
slowing down
parachute opening
at a complete stop
can't wait for the trophy
there it is
it says "CHAMPION" on it
we're dragsters
we're dragsters

Sunday, October 14, 2007

What's New

I'm getting around to adding photos from this past summer.

Check out the posts:

John's rocket

John's etch a sketch drawing of a rocket. A sunday school activity.

More etch-a-sketch art


Saturday, October 13, 2007

Circus Is In Town


Elephants On Parade

Art Center Photos


Our family trip to the Art Center

Photo Albums Online

We're converting our online photos to shutterfly. There is a new web address to make it a little easier: tedncarolyn.shutterfly.com

We'll post links here in this blog whenever we post a new photo album, but you can also browse through the shutterfly pages and just look at old photo albums too.

There's a comment feature here on the blog, and there's also a comment feature on shutterfly. We'll be experimenting with that in the near future too.

Sunday, October 07, 2007

2 Up

Our version of two up means stopping both bikes side by side at a gas pump. Fill two bikes on one swipe of the card.

Saturday, October 06, 2007

Story Inn

Our trip to historic Story, IN and the famous 1851 inn which is still in operation. restaurant, bar, lodging. a destination for bikers and horseback riders who can visit by trails from nearby brown county state park.

One Inconvenient Location Since 1851



Here are pictures of our trip to Story, Indiana.

Thursday, October 04, 2007

Sleep

All wired up for a sleep study. just you watch, i will have a good night's sleep for the first time in months the one night i'm being monitored.

Sunday, September 23, 2007

Sunday Ride To The Park

Always a spectacle in this country to be donning gear. most people ride naked by comparison.

Sunday afternoon family ride to the park.

Sunday, September 02, 2007

A Day At The Park

John shows a 3-inch soft-shelled turtle he caught in the brook.

Also caught that day were crawdads and a water snake.

Saturday, September 01, 2007

Thursday, August 30, 2007

NHRA Nationals

Said John, "That was totally wicked. I'll remember this til I'm 90 years old!"

Best part of the trip was the tour of the pits by Bo, who really knows his stuff. He's been coming here since he was John's age, and he used to race here. Bo is great with John. He explains everything, and is able to answer all John's questions. Bo appreciates how quickly John grasps all things mechanical.



More pictures



Wednesday, August 29, 2007

Emmalee Question

Emmalee turns to Carolyn, and in all seriousness, asks, "How do you get milk from a strawberry?"

Camping Trip 2007



We went to Michigan with Gramma D. The kids first experience camping...

Tuesday, August 28, 2007

State Fair



Kid's Night at the Indiana State Fair

Balloon Launch


I got Emmalee up early on opening day of the state fair so that she and I could sneak out of the house and catch the dawn launch of hot air balloons.


Monday, August 27, 2007

John and Bo bend steel at Bo's shop.

Our New Church

Marching Music?



The Noblesville Marching Millers present the music of The Moody Blues. We saw these T-Shirts at the fair.

I said to Carolyn, "There has to be a band director there who is a Fan..."

EG at the fair on a motorcycle ride.

EG washes her feet in the sink.

Saturday, August 25, 2007

MSNBC Article: A Piece of the Puzzle



Of interest....

I'm especially fascinated by the link between these autism genes and gastro disorders.

Scientists identify a genetic variation that more than doubles the risk of developing autism.
http://www.msnbc.msn.com/id/15338256/site/newsweek/from/ET/



This is a very interesting article about some new research that I thought you might be interested in

Structure Of Protein Altered In Autism

Science Daily As a result of mapping the structure of the protein complex implicated in autism spectrum disorders, a research team led by scientists at the University of California, San Diego (UCSD) Skaggs School of Pharmacy and Pharmaceutical Sciences has discovered how particular genetic mutations affect this complex and contribute to the developmental abnormalities found in children with autism. Their work, published in the June issue of the journal Structure, should help scientists pinpoint the consequences of other genetic abnormalities associated with the disorder.

"By understanding the three-dimensional structure of the normal protein, researchers can now make predictions about how mutations in the gene affect the structure of the gene product," said first author Davide Comoletti, Ph.D., UCSD research associate at the Skaggs School of Pharmacy.

Autism spectrum disorders are developmental disabilities that cause impairments in social interaction and communication. Both children and adults with autism typically show difficulties in verbal and non-verbal communication, interpersonal relationships, and leisure or play activities.

Comoletti and colleagues studied the neuroligin family of proteins that are encoded by genes known to be mutated in certain patients with autism. The neuroligins, and their partner proteins, the neurexins, are involved in the junctions, or synapses, through which cells of the nervous system signal to one another and to non-neuronal tissues such as muscle. These structural studies on neuroligins and neurexins represent a major step toward defining the synaptic organization at the molecular level.

"Normally, individual neuroligins are encoded to interact with specific neurexin partners. The two partners are members of distinct families of proteins involved in synaptic adhesions, imparting 'stickiness' that enables them to associate so that synapses form and have the capacity for neurotransmission," said Palmer Taylor, Ph.D., Dean of the Skaggs School, Sandra & Monroe Trout Professor of Pharmacology, and co-principal investigator of the study, along with Jill Trewhella, Ph.D., of the University of Sydney, Australia and University of Utah.

Incorrect partnering that results when a mutant neuroligin fails to properly align at synapses helps explain why the autism spectrum disorders are manifested in subtle behavioral abnormalities that are seen at an early age.

"Abnormal synaptic development in nerve connections is likely to lead to cognitive deficits seen in patients with autism," said Taylor. He added that synapse formation and maintenance occurs early in development when the infant brain is still plastic and formative. Therefore, by understanding the structural mutations that affect neurotransmission during development, new leads into drug therapies may emerge.

"We really don't know what causes autism, but this research represents a solid starting point," said Sarah Dunsmore, Ph.D., program director with the National Institute of General Medical Sciences, part of the National Institutes of Health, which partly supported the study. "The work suggests that genetic mutations that alter the shape or folding of adhesion proteins in the nervous system influence their interactions. This is another example of how research on basic biological questions, such as the three-dimensional structures of proteins in the brain, can yield valuable medical insights."

Taylor and colleagues have been studying the structure and function of acetylcholinesterase -- a structurally related protein that mediates neurotransmission between nerves and between nerve and muscle -- for the past 30 years. They began studying the neuroligins because of the similarity in structure and amino acid sequence with acetylcholinesterase.

The study was a multi-national collaboration, employing synchrotrons at two national laboratories to collect the X-ray and neutron scattering data necessary for resolving the structure. Additional contributors to this study include Alexander Grishaev, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD; Andrew E. Whitten, Bragg Institute, Australian Nuclear Science and Technology Organization; and Igor Tsigelny, UCSD Department of Pharmacology, Skaggs School of Pharmacy and Pharmaceutical Sciences.

This work was supported in part by grants from the National Institutes of Health, the U.S. Department of Energy, and the Cure Autism Now Foundation.

Note: This story has been adapted from a news release issued by University of California - San Diego.



Saturday, July 07, 2007

Photos